A Potential Diagnostic Marker of Cerebral Amyloid Angiopathy in Alzheimer Disease
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چکیده
Howard H. Feldman, Luis F. Maia, Ian R.A. Mackenzie, Bruce B. Forster, Jeff Angiopathy in Alzheimer Disease Superficial Siderosis : A Potential Diagnostic Marker of Cerebral Amyloid ISSN: 1524-4628 Copyright © 2008 American Heart Association. All rights reserved. Print ISSN: 0039-2499. Online Stroke is published by the American Heart Association. 7272 Greenville Avenue, Dallas, TX 72514 doi: 10.1161/STROKEAHA.107.510826 2008, 39:2894-2897: originally published online July 17, 2008 Stroke http://stroke.ahajournals.org/content/39/10/2894 located on the World Wide Web at: The online version of this article, along with updated information and services, is
منابع مشابه
Superficial siderosis: a potential diagnostic marker of cerebral amyloid angiopathy in Alzheimer disease.
BACKGROUND AND PURPOSE Superficial siderosis of the central nervous system results from chronic bleeding in the superficial layers of the cortex and spinal cord. In cerebral amyloid angiopathy (CAA), there is amyloid deposition in meningeal and meningo-cortical arteries and capillaries, predisposing them to rupture. CAA is frequently associated with Alzheimer disease (AD). METHODS We report a...
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BACKGROUND AND PURPOSE Because the diagnostic significance of cortical superficial siderosis for Alzheimer disease and the association between cortical superficial siderosis and the topographic distribution of cerebral microbleeds have been unclear, we investigated the association between cortical superficial siderosis and clinicoradiologic characteristics of patients with cognitive impairment....
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Cerebral amyloid angiopathy (CAA) is the common term used to define the deposition of amyloid in the walls of medium- and small-size leptomeningeal and cortical arteries, arterioles and, less frequently, capillaries and veins. CAA is an important cause of cerebral hemorrhages although it may also lead to ischemic infarction and dementia. It is a feature commonly associated with normal aging, Al...
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Cerebrovascular disease and Alzheimer disease are common diseases of aging and frequently coexist in the same brain. Accumulating evidence suggests that the presence of brain infarction, including silent infarction, influences the course of Alzheimer disease. Conversely, there is evidence that -amyloid can impair blood vessel function. Vascular -amyloid deposition, also known as cerebral amyloi...
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